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Method Validation and Verification – University of Utah Feb 12, 2018 · •Interference- a significant difference in test result because of another component of the sample •Interfering substance- a substance that causes the measurement to be inaccurate •Can cause a concentration dependent difference in the test •Manufacturers screen for IFS during method development 39 High Performance Liquid Chromatography – 18 Manufacturers High Performance Liquid Chromatography | Chromatographi...

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